- Title
- Role of the Intestinal Epithelium and Its Interaction With the Microbiota in Food Allergy
- Creator
- Ali, Ali; Tan, HuiYing; Kaiko, Gerard E.
- Relation
- NHMRC.APP1162666 & APP1146524 http://purl.org/au-research/grants/nhmrc/1146524
- Relation
- Frontiers in Immunology Vol. 11, Issue December 2020, no. 604054
- Publisher Link
- http://dx.doi.org/10.3389/fimmu.2020.604054
- Publisher
- Frontiers Research Foundation
- Resource Type
- journal article
- Date
- 2020
- Description
- The intestinal epithelial tract forms a dynamic lining of the digestive system consisting of a range of epithelial cell sub-types with diverse functions fulfilling specific niches. The intestinal epithelium is more than just a physical barrier regulating nutrient uptake, rather it plays a critical role in homeostasis through its intrinsic innate immune function, pivotal regulation of antigen sensitization, and a bi-directional interplay with the microbiota that evolves with age. In this review we will discuss these functions of the epithelium in the context of food allergy.
- Subject
- epithelium; microbiota, allergy; allergy, anaphyalaxis; anaphyalaxis; intestinal immunity
- Identifier
- http://hdl.handle.net/1959.13/1444597
- Identifier
- uon:42347
- Identifier
- ISSN:1664-3224
- Language
- eng
- Reviewed
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